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Query: SLC12A7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC12A7 0 0.045 -0.140 -0.110

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC12A7 Ubiquitylation K937 0.559 _SQMLK(gl)QMQLSK_
SLC12A7 Ubiquitylation K1008 -0.028 0.397 _DLFSMK(gl)PDQSNVRR_
SLC12A7 Ubiquitylation K990 0.792 0.282 _LIAEK(gl)YR_
SLC12A7 Phosphorylation T30 0.117 -1.313 _TEAPGT(ph)PEGPEPERPSPGDGNPR_
SLC12A7 Ubiquitylation K976 -0.290 _TQAPPTPDK(gl)VQMTWTR_
SLC12A7 Ubiquitylation K985 0.532 _EK(gl)LIAEK(gl)YR_

Background Information for SLC12A7:


Pubmed-SLC12A7 »
Uniprot-SLC12A7 »
Biogrid-SLC12A7 »
ProteomicsDB-SLC12A7 »

Tumorportal-SLC12A7 »
COSMIC-SLC12A7 »
GenomeRNAi-SLC12A7 »
Genecards-SLC12A7


Protein-protein Interactions for SLC12A7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FSHR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR77 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS9C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NMUR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NRN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTGIR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC17A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNRF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SLC12A7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Na/K/Cl_cotransptS IPR004842 0.09
Category members AA-permease/SLC12A_dom IPR004841 0.08
Category members KCL_cotranspt IPR000076 0


Protein complexes (CORUM database) featuring SLC12A7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SLC12A7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_96 REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 0 0.23
Category members GO Category GO:0006811 ion transport Database 0.18
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0006813 potassium ion transport Database 0.11
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0015377 cation:chloride symporter activity Database 0.03
Category members Pathway Pathway_1207 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES 0 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0006884 cell volume homeostasis Database 0
Category members GO Category GO:0015379 potassium:chloride symporter activity Database 0


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