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Query: SLC12A4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC12A4 1 3.625 2.070 -0.980
SLC12A4 1 3.625 2.070 -0.980 -0.211

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC12A4 Phosphorylation S46 1.095 _ES(ph)SPFLSPLEASR_
SLC12A4 Ubiquitylation K956 0.805 0.863 _EAQLVK(gl)DR_
SLC12A4 Phosphorylation S967 1.069 0.815 _LESLYS(ph)DEEDESAVGADK_
SLC12A4 Phosphorylation S1032 1.073 0.731 _LTSIGS(ph)DEDEETETYQEK_
SLC12A4 Phosphorylation S1029 -0.062 0.275 _LTS(ph)IGSDEDEETETYQEK_
SLC12A4 Phosphorylation S32 0.017 0.114 _IDDIPGLSDTS(ph)PDLSSR_
SLC12A4 Phosphorylation T1028 -0.062 -0.199 _LT(ph)SIGSDEDEETETYQEK_
SLC12A4 Ubiquitylation K1012 0.029 -0.446 _ELVHIK(gl)PDQSNVRR_
SLC12A4 Phosphorylation T31 0.337 _IDDIPGLSDT(ph)SPDLSSR_
SLC12A4 Ubiquitylation K99 0.351 _LVSYTNLTQGAK(gl)EHEEAESGEGTR_
SLC12A4 Phosphorylation S47 -0.556 _ESS(ph)PFLSPLEASR_

Background Information for SLC12A4:


Pubmed-SLC12A4 »
Uniprot-SLC12A4 »
Biogrid-SLC12A4 »
ProteomicsDB-SLC12A4 »

Tumorportal-SLC12A4 »
COSMIC-SLC12A4 »
GenomeRNAi-SLC12A4 »
Genecards-SLC12A4


Protein-protein Interactions for SLC12A4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHRND Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM189A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM189B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL17RC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS9C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NRN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHB16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTH1R Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC17A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF10A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SLC12A4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members K/Cl_cotranspt1 IPR000622 0.29
Category members K/Cl_cotranspt_1/3 IPR018491 0.29
Category members Na/K/Cl_cotransptS IPR004842 0.09
Category members AA-permease/SLC12A_dom IPR004841 0.08
Category members ClpP/crotonase-like_dom IPR029045 0.08
Category members KCL_cotranspt IPR000076 0


Protein complexes (CORUM database) featuring SLC12A4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SLC12A4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_96 REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 0 0.23
Category members GO Category GO:0006811 ion transport Database 0.18
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0006813 potassium ion transport Database 0.11
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0015377 cation:chloride symporter activity Database 0.03
Category members Pathway Pathway_1207 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES 0 0
Category members GO Category GO:0005215 transporter activity Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0006884 cell volume homeostasis Database 0
Category members GO Category GO:0015379 potassium:chloride symporter activity Database 0


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