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Query: SKA2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SKA2 0 -1.108 0.160 -0.730

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SKA2 Ubiquitylation K54 -1.108 _ELSVIK(gl)SR_
SKA2 Ubiquitylation K72 -1.463 _FKPVAVEQK(gl)ESK_

Background Information for SKA2:





Protein-protein Interactions for SKA2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SKA3 Cat. description Hein, Mann, Cell 2015
Category members IP bait HAUS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RALYL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SKA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SKA2

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring SKA2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SKA2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0051301 cell division Database 1.15
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0005876 spindle microtubule Database 0.68
Category members GO Category GO:0031110 regulation of microtubule polymerization or depolymerization Database 0.35
Category members GO Category GO:0000940 condensed chromosome outer kinetochore Database 0.18
Category members GO Category GO:0007059 chromosome segregation Database 0.13


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