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Query: SIPA1L3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SIPA1L3 1 4.344 -0.750 0.380 0.397 0.037 -0.084

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SIPA1L3 Ubiquitylation K1515 1.582 _STIEDDLK(gl)K_
SIPA1L3 Ubiquitylation K1516 1.582 _STIEDDLK(gl)K_
SIPA1L3 Phosphorylation S1544 0.985 1.047 _TLS(ph)DESLCSGR_
SIPA1L3 Phosphorylation S1364 -0.112 -0.154 _EVS(ph)PAPAVAGQSK_
SIPA1L3 Phosphorylation T1705 -0.178 _TTPT(ph)MSEEPPLDLTGK_
SIPA1L3 Phosphorylation T1703 -0.192 _TT(ph)PTMSEEPPLDLTGK_
SIPA1L3 Phosphorylation T1702 -0.665 _T(ph)TPTM(ox)SEEPPLDLTGK_

Background Information for SIPA1L3:


Pubmed-SIPA1L3 »
Uniprot-SIPA1L3 »
Biogrid-SIPA1L3 »
ProteomicsDB-SIPA1L3 »

Tumorportal-SIPA1L3 »
COSMIC-SIPA1L3 »
GenomeRNAi-SIPA1L3 »
Genecards-SIPA1L3


Protein-protein Interactions for SIPA1L3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC26 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK5RAP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP135 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait COPA Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNC1LI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TOR1AIP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LZTS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR83 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SIPA1L3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PDZ IPR001478 0.15
Category members Rap_GAP_dom IPR000331 0.02
Category members DUF3401 IPR021818 0


Protein complexes (CORUM database) featuring SIPA1L3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SIPA1L3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members GO Category GO:0005096 GTPase activator activity Database 0.19


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