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Query: SEPN1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SEPN1 0 -0.691 0.200 0.000

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SEPN1 Ubiquitylation K174 -0.691 _SK(gl)DGFLGVSR_
SEPN1 Ubiquitylation K426 -0.882 _RLEVAM(ox)YPFK(gl)K_
SEPN1 Ubiquitylation K427 -0.882 _RLEVAM(ox)YPFK(gl)K_

Background Information for SEPN1:





Protein-protein Interactions for SEPN1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHST8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FEZ1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HLA-DRB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LACRT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYZL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OS9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PEX19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PROZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGB2A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ST8SIA5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR5B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SEPN1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members EF_hand_dom IPR002048 0


Protein complexes (CORUM database) featuring SEPN1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SEPN1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members Disease phenotype Congenital_fiber-type_disproportion_myopathy Congenital fiber-type disproportion myopathy Database 0.04
Category members Disease phenotype Classic_multiminicore_myopathy Classic multiminicore myopathy Database 0
Category members GO Category GO:0008150 biological_process Database 0


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