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Query: RPS8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RPS8 2 8.600 -1.140 2.070 -0.007 0.149 -0.081 -0.311 0.128

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RPS8 Ubiquitylation K157 1.193 1.628 _NAK(gl)ISSLLEEQFQQGK_
RPS8 Ubiquitylation K139 -0.125 1.300 _LTPEEEEILNK(gl)KR_
RPS8 Ubiquitylation K140 0.203 1.207 _LTPEEEEILNKK(gl)R_
RPS8 Phosphorylation T130 3.051 0.780 _LT(ph)PEEEEILNKK_
RPS8 Ubiquitylation K128 0.328 0.619 _GAK(gl)LTPEEEEILNK_
RPS8 Ubiquitylation K37 0.117 0.580 _YELGRPAANTK(gl)IGPR_

Background Information for RPS8:


Pubmed-RPS8 »
Uniprot-RPS8 »
Biogrid-RPS8 »
ProteomicsDB-RPS8 »

Tumorportal-RPS8 »
COSMIC-RPS8 »
GenomeRNAi-RPS8 »
Genecards-RPS8


Protein-protein Interactions for RPS8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CBX8 Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3E Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait IBTK Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP9 Cat. description Hein, Mann, Cell 2015
Category members IP bait NPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait CNBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGCR8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait E4F1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EBNA1BP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MECP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MKI67IP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL28 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL28 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL37A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SART3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RPS8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ribosomal_S8e/biogenesis_NSA2 IPR022309 0


Protein complexes (CORUM database) featuring RPS8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF
Category members Corum 306 Ribosome, cytoplasmic Database INF
Category members Corum 338 40S ribosomal subunit, cytoplasmic Database 11.21
Category members Corum 305 40S ribosomal subunit, cytoplasmic Database 10.7


Categories featuring RPS8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members Pathway Pathway_369 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION 0 INF
Category members Pathway Pathway_371 REACTOME_INFLUENZA_LIFE_CYCLE 0 INF
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members Pathway Pathway_459 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 0 INF
Category members Pathway Pathway_768 REACTOME_PEPTIDE_CHAIN_ELONGATION 0 INF
Category members Pathway Pathway_769 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX 0 INF
Category members Pathway Pathway_770 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 0 INF
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_772 KEGG_RIBOSOME 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members Pathway Pathway_774 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION 0 INF
Category members GO Category GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Database INF
Category members GO Category GO:0003735 structural constituent of ribosome Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006413 translational initiation Database INF
Category members GO Category GO:0006414 translational elongation Database INF
Category members GO Category GO:0006415 translational termination Database INF
Category members GO Category GO:0006614 SRP-dependent cotranslational protein targeting to membrane Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members GO Category GO:0019058 viral life cycle Database INF
Category members GO Category GO:0019083 viral transcription Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005840 ribosome Database 12.2
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members Pathway Pathway_775 REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S 0 11.53
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0022627 cytosolic small ribosomal subunit Database 9.14
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members GO Category GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Database 0.38
Category members GO Category GO:0005622 intracellular Database 0.32


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