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Query: RPS19

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RPS19 2 7.551 -0.740 0.700 0.293 -0.521 0.362 -0.002 0.056

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RPS19 Ubiquitylation K155 4.833 2.193 _IAGQVAAANK(gl)KH_
RPS19 Ubiquitylation K89 1.992 _GGAGVGSMTK(gl)IYGGR_
RPS19 Ubiquitylation K36 0.743 1.223 _ALAAFLKK(gl)_
RPS19 Ubiquitylation K19 0.002 1.071 _PGVTVK(gl)DVNQQEFVR_
RPS19 Ubiquitylation K156 4.100 _IAGQVAAANK(gl)KH_

Background Information for RPS19:


Pubmed-RPS19 »
Uniprot-RPS19 »
Biogrid-RPS19 »
ProteomicsDB-RPS19 »

Tumorportal-RPS19 »
COSMIC-RPS19 »
GenomeRNAi-RPS19 »
Genecards-RPS19


Protein-protein Interactions for RPS19
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EIF3A Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3E Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait NPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait HIST1H1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RPS19
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring RPS19
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 306 Ribosome, cytoplasmic Database INF
Category members Corum 338 40S ribosomal subunit, cytoplasmic Database 11.21
Category members Corum 305 40S ribosomal subunit, cytoplasmic Database 10.7


Categories featuring RPS19
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_369 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION 0 INF
Category members Pathway Pathway_371 REACTOME_INFLUENZA_LIFE_CYCLE 0 INF
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members Pathway Pathway_459 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 0 INF
Category members Pathway Pathway_768 REACTOME_PEPTIDE_CHAIN_ELONGATION 0 INF
Category members Pathway Pathway_769 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX 0 INF
Category members Pathway Pathway_770 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 0 INF
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_772 KEGG_RIBOSOME 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members Pathway Pathway_774 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION 0 INF
Category members GO Category GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Database INF
Category members GO Category GO:0003735 structural constituent of ribosome Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006413 translational initiation Database INF
Category members GO Category GO:0006414 translational elongation Database INF
Category members GO Category GO:0006415 translational termination Database INF
Category members GO Category GO:0006614 SRP-dependent cotranslational protein targeting to membrane Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members GO Category GO:0019058 viral life cycle Database INF
Category members GO Category GO:0019083 viral transcription Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005840 ribosome Database 12.2
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members Pathway Pathway_775 REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S 0 11.53
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0022627 cytosolic small ribosomal subunit Database 9.14
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006364 rRNA processing Database 2.47
Category members Disease phenotype Blackfan-Diamond_anemia Blackfan-Diamond anemia Database 2.38
Category members GO Category GO:0042274 ribosomal small subunit biogenesis Database 1.64
Category members GO Category GO:0030490 maturation of SSU-rRNA Database 0.98
Category members GO Category GO:0051262 protein tetramerization Database 0.6
Category members GO Category GO:0051272 positive regulation of cellular component movement Database 0.46
Category members GO Category GO:0000028 ribosomal small subunit assembly Database 0.39
Category members GO Category GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Database 0.38
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0007000 nucleolus organization Database 0.18
Category members GO Category GO:0030218 erythrocyte differentiation Database 0.13
Category members GO Category GO:0060265 positive regulation of respiratory burst involved in inflammatory response Database 0.08
Category members GO Category GO:0002548 monocyte chemotaxis Database 0
Category members GO Category GO:0009991 response to extracellular stimulus Database 0
Category members GO Category GO:0017134 fibroblast growth factor binding Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0060266 negative regulation of respiratory burst involved in inflammatory response Database 0


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