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Query: RPL3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RPL3 2 8.722 -0.360 0.140 0.438 0.956 0.791 -0.157 0.175

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RPL3 Ubiquitylation K155 3.248 2.633 _K(gl)YCQVIR_
RPL3 Ubiquitylation K300 2.079 2.310 _LIK(gl)NNASTDYDLSDK_
RPL3 Ubiquitylation K386 3.041 2.290 _FQTMEEKK(gl)_
RPL3 Ubiquitylation K373 3.746 2.288 _FIDTTSK(gl)FGHGR_
RPL3 Ubiquitylation K294 2.502 2.279 _IGQGYLIK(gl)DGK_
RPL3 Ubiquitylation K132 2.258 2.249 _AFTK(gl)YCK_
RPL3 Ubiquitylation K362 3.094 2.199 _ALEK(gl)IDLK_
RPL3 Ubiquitylation K366 1.984 2.196 _IDLK(gl)FIDTTSK_
RPL3 Ubiquitylation K356 2.807 2.163 _SLLVQTK(gl)R_
RPL3 Ubiquitylation K286 0.633 1.077 _IYK(gl)IGQGYLIK_
RPL3 Ubiquitylation K115 1.354 0.934 _TVFAEHISDECK(gl)R_
RPL3 Ubiquitylation K66 2.563 _EVDRPGSK(gl)VNKK_
RPL3 Ubiquitylation K297 3.282 _IGQGYLIKDGK(gl)LIK_
RPL3 Ubiquitylation K341 2.463 _GCVVGTK(gl)KR_
RPL3 Ubiquitylation K385 3.041 _FQTMEEK(gl)K_

Background Information for RPL3:


Pubmed-RPL3 »
Uniprot-RPL3 »
Biogrid-RPL3 »
ProteomicsDB-RPL3 »

Tumorportal-RPL3 »
COSMIC-RPL3 »
GenomeRNAi-RPL3 »
Genecards-RPL3


Protein-protein Interactions for RPL3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BRWD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3A Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3E Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait NPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait BHLHA15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C16orf88 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CNBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPNE4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EBNA1BP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GLTSCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA0020 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGEB10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAK16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MECP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPAN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRR11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM4B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL18A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL28 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL30 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL37A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRP8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SART3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SRP68 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR55 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBTB48 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF324B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RPL3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Transl_B-barrel IPR009000 0.24
Category members Ribosomal_L3 IPR000597 0.14


Protein complexes (CORUM database) featuring RPL3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF
Category members Corum 306 Ribosome, cytoplasmic Database INF
Category members Corum 308 60S ribosomal subunit, cytoplasmic Database INF


Categories featuring RPL3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_369 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION 0 INF
Category members Pathway Pathway_371 REACTOME_INFLUENZA_LIFE_CYCLE 0 INF
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members Pathway Pathway_459 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 0 INF
Category members Pathway Pathway_768 REACTOME_PEPTIDE_CHAIN_ELONGATION 0 INF
Category members Pathway Pathway_770 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 0 INF
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_772 KEGG_RIBOSOME 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members Pathway Pathway_774 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION 0 INF
Category members GO Category GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Database INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0003735 structural constituent of ribosome Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006413 translational initiation Database INF
Category members GO Category GO:0006414 translational elongation Database INF
Category members GO Category GO:0006415 translational termination Database INF
Category members GO Category GO:0006614 SRP-dependent cotranslational protein targeting to membrane Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members GO Category GO:0019058 viral life cycle Database INF
Category members GO Category GO:0019083 viral transcription Database INF
Category members GO Category GO:0022625 cytosolic large ribosomal subunit Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005840 ribosome Database 12.2
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0071353 cellular response to interleukin-4 Database 0.19


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