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Query: RNF6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RNF6 0 0.477 0.190 -0.490

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RNF6 Ubiquitylation K608 0.477 _GLTK(gl)EQIDNLSTR_

Background Information for RNF6:


Pubmed-RNF6 »
Uniprot-RNF6 »
Biogrid-RNF6 »
ProteomicsDB-RNF6 »

Tumorportal-RNF6 »
COSMIC-RNF6 »
GenomeRNAi-RNF6 »
Genecards-RNF6


Protein-protein Interactions for RNF6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RNF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RNF6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_RING IPR001841 0
Category members Znf_C3HC4_RING-type IPR018957 0


Protein complexes (CORUM database) featuring RNF6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RNF6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0016605 PML body Database 1.41
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0030424 axon Database 0.23
Category members GO Category GO:0044314 protein K27-linked ubiquitination Database 0.13
Category members GO Category GO:0050681 androgen receptor binding Database 0.12
Category members Disease phenotype ESOPHAGEAL_CANCER ESOPHAGEAL CANCER Database 0.05
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0030517 negative regulation of axon extension Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0060765 regulation of androgen receptor signaling pathway Database 0
Category members GO Category GO:0070936 protein K48-linked ubiquitination Database 0


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