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bioLOGIC Data

Query: RNF138

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
RNF138	0	-1.152	-0.630	1.230				-0.438	-0.954

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
RNF138	Ubiquitylation	K158	-0.990		_SETSTSDNTETYQENTSSSGHPTFK(gl)CPLCQESNFTR_

Background Information for RNF138:

Pubmed-RNF138 »

Uniprot-RNF138 »

Biogrid-RNF138 »

ProteomicsDB-RNF138 »

Tumorportal-RNF138 »

COSMIC-RNF138 »

GenomeRNAi-RNF138 »

Genecards-RNF138

Protein-protein Interactions for RNF138

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait ARIH1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait BZW1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait C16orf71	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CCDC120	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait COPS8	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CPNE2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait FAM136A	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait FRYL	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait GPR156	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait JMJD6	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MAPK14	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait NAP1L5	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait NECAB1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait PRICKLE3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TNFRSF1A	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TRPV5	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TULP3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait UBE2K	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait WDR4	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in RNF138

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	Znf_MIZ	IPR004181	0.13
Category members	Znf_RING	IPR001841	0
Category members	Znf_C3HC4_RING-type	IPR018957	0

Protein complexes (CORUM database) featuring RNF138

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring RNF138

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	Pathway	Pathway_621	REACTOME_ADAPTIVE_IMMUNE_SYSTEM	0	4.72
Category members	Pathway	Pathway_458	REACTOME_IMMUNE_SYSTEM	0	3
Category members	Pathway	Pathway_764	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	0	2.56
Category members	Pathway	Pathway_832	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	0	1.58
Category members	GO Category	GO:0019901	protein kinase binding	Database	0.37
Category members	GO Category	GO:0008270	zinc ion binding	Database	0.29
Category members	GO Category	GO:0016055	Wnt signaling pathway	Database	0.11
Category members	GO Category	GO:0016567	protein ubiquitination	Database	0.07
Category members	GO Category	GO:0016874	ligase activity	Database	0
Category members	GO Category	GO:0046872	metal ion binding	Database	0