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Query: RCC2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RCC2 0 2.252 0.410 -0.620 0.375 0.191 0.577

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RCC2 Ubiquitylation K377 -0.419 0.522 _LVK(gl)LFDFPGR_
RCC2 Ubiquitylation K349 0.587 0.393 _DVACGANHTLVLDSQK(gl)R_
RCC2 Ubiquitylation K92 -1.060 -0.648 _AGGAAVVITEPEHTK(gl)ER_
RCC2 Ubiquitylation K320 -0.668 -1.772 _TK(gl)DGQILPVPNVVVR_
RCC2 Ubiquitylation K124 -0.421 _EVPK(gl)QQAAYR_
RCC2 Ubiquitylation K368 -0.289 _LGHAEQK(gl)DEMVPR_

Background Information for RCC2:


Pubmed-RCC2 »
Uniprot-RCC2 »
Biogrid-RCC2 »
ProteomicsDB-RCC2 »

Tumorportal-RCC2 »
COSMIC-RCC2 »
GenomeRNAi-RCC2 »
Genecards-RCC2


Protein-protein Interactions for RCC2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait NEDD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PHF8 Cat. description Hein, Mann, Cell 2015
Category members IP bait RACGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait SUMO3 Cat. description Hein, Mann, Cell 2015
Category members IP bait VWA9 Cat. description Hein, Mann, Cell 2015
Category members IP bait DEF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RCC2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RCC1/BLIP-II IPR009091 0.24
Category members Reg_chr_condens IPR000408 0.23


Protein complexes (CORUM database) featuring RCC2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RCC2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0005819 spindle Database 0.41
Category members GO Category GO:0000775 chromosome, centromeric region Database 0.29


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