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Query: RBM15

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RBM15 2 9.340 -1.840 3.710 0.149 0.626 0.647 0.721 0.292

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RBM15 Phosphorylation S127 2.364 0.831 _LHSYS(ph)SPSTK_
RBM15 Phosphorylation S109 0.735 0.709 _GGS(ph)REYDTGGGSSSSR_
RBM15 Phosphorylation S294 0.496 0.464 _SLS(ph)PGGAALGYR_
RBM15 Phosphorylation T568 0.217 0.371 _DRT(ph)PPLLYR_
RBM15 Phosphorylation S656 0.197 _HLDRS(ph)PESDRPR_
RBM15 Phosphorylation S700 -0.166 0.067 _LLLERPS(ph)PIRDR_
RBM15 Phosphorylation S741 -0.059 0.023 _TTAPTEGKS(ph)PLKK_
RBM15 Phosphorylation S670 0.323 0.021 _HCAPS(ph)PDRSPELSSSR_
RBM15 Phosphorylation S765 -0.276 -0.017 _LKS(ph)PSQKQDGGTAPVASASPK_
RBM15 Phosphorylation S128 -0.113 -0.328 _LHSYSS(ph)PSTK_

Background Information for RBM15:


Pubmed-RBM15 »
Uniprot-RBM15 »
Biogrid-RBM15 »
ProteomicsDB-RBM15 »

Tumorportal-RBM15 »
COSMIC-RBM15 »
GenomeRNAi-RBM15 »
Genecards-RBM15


Protein-protein Interactions for RBM15
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CEP170P1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYC Cat. description Hein, Mann, Cell 2015
Category members IP bait PFKFB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MUC20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCKIPSD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PMEL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM15B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TOR1AIP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3H18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RBM15
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members SPOC_C IPR012921 1.41
Category members SPOC_like_C_dom IPR016194 0.9
Category members SPOC_met IPR010912 0.52


Protein complexes (CORUM database) featuring RBM15
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3


Categories featuring RBM15
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0045638 negative regulation of myeloid cell differentiation Database 0.1
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0001569 patterning of blood vessels Database 0
Category members GO Category GO:0007221 positive regulation of transcription of Notch receptor target Database 0
Category members GO Category GO:0048536 spleen development Database 0
Category members GO Category GO:0060412 ventricular septum morphogenesis Database 0
Category members GO Category GO:0060674 placenta blood vessel development Database 0


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