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Query: RBM10

This is a cancer-associated gene according to the Broad cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RBM10 0 3.588 -0.560 0.940 0.778 -0.520 -0.016 -0.006 0.266

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RBM10 Phosphorylation S862 1.175 _AHLS(ph)ENELEALEKNDMEQMK_
RBM10 Phosphorylation S801 0.197 0.491 _GLVAAYSGES(ph)DSEEEQER_
RBM10 Phosphorylation S910 0.971 -0.069 _YGGISTAS(ph)VDFEQPTR_
RBM10 Phosphorylation S154 -0.002 -0.114 _HS(ph)PTGPPGFPR_
RBM10 Phosphorylation S788 -0.557 -0.505 _LASDDRPS(ph)PPR_
RBM10 Phosphorylation S30 0.831 _GGGESLQEAS(ph)PR_
RBM10 Phosphorylation S783 -0.098 _LAS(ph)DDRPSPPR_

Background Information for RBM10:


Pubmed-RBM10 »
Uniprot-RBM10 »
Biogrid-RBM10 »
ProteomicsDB-RBM10 »

Tumorportal-RBM10 »
COSMIC-RBM10 »
GenomeRNAi-RBM10 »
Genecards-RBM10


Protein-protein Interactions for RBM10
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDKN2AIP Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK2A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait EMC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ENTHD2 Cat. description Hein, Mann, Cell 2015
Category members IP bait HUWE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ITGB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait MIS12 Cat. description Hein, Mann, Cell 2015
Category members IP bait MMGT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MPP6 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait NAA11 Cat. description Hein, Mann, Cell 2015
Category members IP bait PARD6B Cat. description Hein, Mann, Cell 2015
Category members IP bait SGOL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SHOC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait TIMELESS Cat. description Hein, Mann, Cell 2015
Category members IP bait TRIP11 Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait RBM17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RBM10
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members Znf_C2H2 IPR007087 0.92
Category members Znf_RanBP2 IPR001876 0.18
Category members G_patch_dom IPR000467 0.09


Protein complexes (CORUM database) featuring RBM10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RBM10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members Human mutations Broad_cancer_genes Broad cancer genes (Lawrence et al., 2014) literature 1.14
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0008150 biological_process Database 0
Category members GO Category GO:0034391 regulation of smooth muscle cell apoptotic process Database 0
Category members GO Category GO:0034393 positive regulation of smooth muscle cell apoptotic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0070935 3'-UTR-mediated mRNA stabilization Database 0


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