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Query: RANGAP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RANGAP1 0 3.877 -1.290 1.580
RANGAP1 0 3.877 -1.290 1.580 0.733 0.687 0.344 0.751 0.311

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RANGAP1 Ubiquitylation K481 -0.208 0.739 _VSSVFK(gl)DEATVR_
RANGAP1 Ubiquitylation K261 0.736 _GAVAMAETLK(gl)TLR_
RANGAP1 Ubiquitylation K279 -0.152 0.129 _SK(gl)GAVAIADAIR_
RANGAP1 Phosphorylation S387 -2.181 -0.260 _KILDPNTGEPAPVLSS(ph)PPPADVSTFLAFPS(ph)PEK_
RANGAP1 Phosphorylation S373 -1.922 -1.160 _ILDPNTGEPAPVLSS(ph)PPPADVSTFLAFPSPEK_
RANGAP1 Phosphorylation S372 -1.467 -1.791 _KILDPNTGEPAPVLS(ph)SPPPADVSTFLAFPSPEK_
RANGAP1 Phosphorylation S380 -1.900 _ILDPNTGEPAPVLSSPPPADVS(ph)TFLAFPSPEK_
RANGAP1 Ubiquitylation K15 -0.280 _LAETLAK(gl)TQVAGGQLSFK_
RANGAP1 Ubiquitylation K28 0.419 _TQVAGGQLSFKGK(gl)_
RANGAP1 Ubiquitylation K296 0.459 _LK(gl)ELNLSFCEIKR_
RANGAP1 Ubiquitylation K452 -0.941 _LGPK(gl)SSVLIAQQTDTSDPEK_

Background Information for RANGAP1:


Pubmed-RANGAP1 »
Uniprot-RANGAP1 »
Biogrid-RANGAP1 »
ProteomicsDB-RANGAP1 »

Tumorportal-RANGAP1 »
COSMIC-RANGAP1 »
GenomeRNAi-RANGAP1 »
Genecards-RANGAP1


Protein-protein Interactions for RANGAP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP6AP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN4 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNLRB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIFC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP107 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP153 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP155 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP214 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP98 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKAA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RANBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEH1L Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2I Cat. description Hein, Mann, Cell 2015
Category members IP bait B2M Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RCC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM194A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBE2I Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RANGAP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Leu-rich_rpt_RNase_inh_sub-typ IPR003590 0.06


Protein complexes (CORUM database) featuring RANGAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RANGAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_196 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 0 9.67
Category members Pathway Pathway_376 REACTOME_HIV_LIFE_CYCLE 0 9.45
Category members Pathway Pathway_374 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 0 7.57
Category members GO Category GO:0005643 nuclear pore Database 6.58
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0000776 kinetochore Database 2.24
Category members Pathway Pathway_1254 PID_RANBP2_PATHWAY 0 1.33
Category members Pathway Pathway_943 PID_HDAC_CLASSI_PATHWAY 0 1.08
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members Pathway Pathway_1255 BIOCARTA_RANMS_PATHWAY 0 0.35
Category members GO Category GO:0000922 spindle pole Database 0.35
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members Pathway Pathway_1143 PID_HDAC_CLASSII_PATHWAY 0 0.3
Category members GO Category GO:0046826 negative regulation of protein export from nucleus Database 0.23
Category members GO Category GO:0007165 signal transduction Database 0


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