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Query: RALY

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RALY 3 3.494 2.260 -0.770
RALY 3 3.494 2.260 -0.770 0.238 -0.951 0.007 0.045 0.239

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RALY Phosphorylation T298 1.615 _TRDDGDEEGLLTHS(ph)EEELEHSQDT(ph)DADDGALQ_
RALY Phosphorylation S295 1.157 _TRDDGDEEGLLTHSEEELEHS(ph)QDTDADDGALQ_
RALY Ubiquitylation K13 1.146 0.587 _LQASNVTNK(gl)NDPK_
RALY Ubiquitylation K35 0.952 0.299 _VFIGNLNTALVKK(gl)_
RALY Ubiquitylation K4 -0.148 0.151 _(ac)SLK(gl)LQASNVTNKNDPK_
RALY Phosphorylation S288 -1.196 -1.015 _TRDDGDEEGLLTHS(ph)EEELEHSQDTDADDGALQ_
RALY Phosphorylation S135 -0.847 -1.137 _LS(ph)PVPVPR_
RALY Ubiquitylation K34 0.952 _VFIGNLNTALVK(gl)K_
RALY Ubiquitylation K44 0.562 _KSDVETIFSK(gl)YGR_
RALY Ubiquitylation K146 0.856 _AVPVK(gl)RPR_
RALY Ubiquitylation K165 0.213 _TNVPVK(gl)LFAR_
RALY Ubiquitylation K181 1.617 _STAVTTSSAKIK(gl)_
RALY Ubiquitylation K216 0.457 _LEQIAAEQK(gl)ANPDGK_
RALY Phosphorylation T286 -1.169 _TRDDGDEEGLLT(ph)HSEEELEHSQDTDADDGALQ_

Background Information for RALY:





Protein-protein Interactions for RALY

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HNRNPA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait APOBEC3D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C11orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGCR8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXW11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HNRNPA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ILF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSME3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RALYL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STAU1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STRBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3H18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZFC3H1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RALY

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members hnRNP_C_Raly IPR017347 0.89


Protein complexes (CORUM database) featuring RALY

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1181 C complex spliceosome Database 2.39
Category members Corum 1332 Large Drosha complex Database 0.08


Categories featuring RALY

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0003676 nucleic acid binding Database 0.83


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