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Query: QARS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
QARS 1 6.886 1.350 -0.720 0.505 4.502
QARS 1 6.886 1.350 -0.720 -0.046 0.058 0.298

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
QARS Ubiquitylation K25 0.712 _ETLK(gl)NSALSAQLR_
QARS Ubiquitylation K158 0.649 _AVLK(gl)WADGK_
QARS Ubiquitylation K412 -0.265 _LVMEDGK(gl)MDPVAYR_
QARS Ubiquitylation K628 -1.147 _TDFKEEPEPGFK(gl)R_
QARS Ubiquitylation K187 0.858 _LEADLEK(gl)K_
QARS Ubiquitylation K188 0.858 _LEADLEK(gl)K_

Background Information for QARS:


Pubmed-QARS »
Uniprot-QARS »
Biogrid-QARS »
ProteomicsDB-QARS »

Tumorportal-QARS »
COSMIC-QARS »
GenomeRNAi-QARS »
Genecards-QARS


Protein-protein Interactions for QARS
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SDCCAG8 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2K Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait KARS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPM1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait QARS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDCBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in QARS
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ribosomal_L25/Gln-tRNA_synth IPR011035 0.31
Category members Glu/Gln-tRNA-synth_Ib_codon-bd IPR020059 0.31
Category members Glu/Gln-tRNA-synth IPR000924 0.09
Category members Glu/Gln-tRNA-synth_Ib_cat-dom IPR020058 0.09


Protein complexes (CORUM database) featuring QARS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3040 Multisynthetase complex Database 1.78


Categories featuring QARS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_201 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION 0 3.57
Category members Pathway Pathway_202 REACTOME_TRNA_AMINOACYLATION 0 1.34
Category members GO Category GO:0006418 tRNA aminoacylation for protein translation Database 0.91
Category members Pathway Pathway_409 KEGG_AMINOACYL_TRNA_BIOSYNTHESIS 0 0.82
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds Database 0.42
Category members GO Category GO:0004812 aminoacyl-tRNA ligase activity Database 0.41
Category members Pathway Pathway_203 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION 0 0
Category members GO Category GO:0043039 tRNA aminoacylation Database 0


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