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Query: PYCRL

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PYCRL 0 1.004 -0.860 0.620

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PYCRL Ubiquitylation K44 0.384 _AGK(gl)VEAQHILASAPTDR_

Background Information for PYCRL:


Pubmed-PYCRL »
Uniprot-PYCRL »
Biogrid-PYCRL »
ProteomicsDB-PYCRL »

Tumorportal-PYCRL »
COSMIC-PYCRL »
GenomeRNAi-PYCRL »
Genecards-PYCRL


Protein-protein Interactions for PYCRL
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait TP53BP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCMT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PYCR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PYCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PYCRL
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members 6-PGluconate_DH_C-like IPR008927 0.51
Category members Pyrroline-COOH_reductase IPR000304 0
Category members ProC_N IPR028939 0


Protein complexes (CORUM database) featuring PYCRL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PYCRL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members Pathway Pathway_135 KEGG_ARGININE_AND_PROLINE_METABOLISM 0 0.01
Category members GO Category GO:0004735 pyrroline-5-carboxylate reductase activity Database 0
Category members GO Category GO:0006561 proline biosynthetic process Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0
Category members GO Category GO:0055129 L-proline biosynthetic process Database 0


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