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Query: PYCR2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PYCR2 0 -3.503 -0.388 -0.506 -0.405 -0.139 -0.115

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PYCR2 Ubiquitylation K284 -0.378 _ISPAALKK(gl)_
PYCR2 Phosphorylation S304 -0.660 -0.912 _LESPTVSTLTPSS(ph)PGK_

Background Information for PYCR2:


Pubmed-PYCR2 »
Uniprot-PYCR2 »
Biogrid-PYCR2 »
ProteomicsDB-PYCR2 »

Tumorportal-PYCR2 »
COSMIC-PYCR2 »
GenomeRNAi-PYCR2 »
Genecards-PYCR2


Protein-protein Interactions for PYCR2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANAPC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait AR Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC16 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC23 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP85L Cat. description Hein, Mann, Cell 2015
Category members IP bait PDK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PYCR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PYCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PYCR2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members 6-PGluconate_DH_C-like IPR008927 0.51
Category members Pyrroline-COOH_reductase IPR000304 0
Category members G3P_DH_NAD-dep_N IPR011128 0
Category members ProC_N IPR028939 0


Protein complexes (CORUM database) featuring PYCR2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PYCR2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_135 KEGG_ARGININE_AND_PROLINE_METABOLISM 0 0.01
Category members GO Category GO:0004735 pyrroline-5-carboxylate reductase activity Database 0
Category members GO Category GO:0006561 proline biosynthetic process Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0
Category members GO Category GO:0055129 L-proline biosynthetic process Database 0


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