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Query: PWP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PWP1 0 0.684 0.270 -0.400 1.306 -0.779 -1.621 -0.127

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PWP1 Phosphorylation S57 0.195 0.392 _LQEEGGGS(ph)DEEETGS(ph)PSEDGMQSAR_
PWP1 Phosphorylation S50 0.089 0.204 _LQEEGGGS(ph)DEEETGSPSEDGMQSAR_
PWP1 Phosphorylation T55 0.309 0.118 _LQEEGGGSDEEET(ph)GS(ph)PSEDGM(ox)QSAR_
PWP1 Ubiquitylation K29 1.204 _ETPDKVELSK(gl)EEVKR_
PWP1 Ubiquitylation K33 0.216 _ETPDKVELSKEEVK(gl)R_
PWP1 Ubiquitylation K42 0.921 _LIAEAKEK(gl)_

Background Information for PWP1:


Pubmed-PWP1 »
Uniprot-PWP1 »
Biogrid-PWP1 »
ProteomicsDB-PWP1 »

Tumorportal-PWP1 »
COSMIC-PWP1 »
GenomeRNAi-PWP1 »
Genecards-PWP1


Protein-protein Interactions for PWP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait PWP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PWP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members G-protein_beta_WD-40_rep IPR020472 0.12


Protein complexes (CORUM database) featuring PWP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF


Categories featuring PWP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07


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