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Query: PTDSS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PTDSS1 1 2.862 -0.730 0.720 0.172 0.354

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PTDSS1 Ubiquitylation K348 1.727 _QYYAYLTDTQCK(gl)R_
PTDSS1 Ubiquitylation K12 0.016 1.022 _TLSK(gl)DDVNYK_
PTDSS1 Ubiquitylation K259 0.961 _DIHTTTGK(gl)IKR_
PTDSS1 Ubiquitylation K281 -0.300 0.696 _WFDPK(gl)SSFQR_
PTDSS1 Phosphorylation S439 -1.539 -0.129 _GS(ph)EDSPPKHAGNNESHSSR_
PTDSS1 Phosphorylation S442 0.002 -0.209 _GSEDS(ph)PPKHAGNNESHSSR_

Background Information for PTDSS1:


Pubmed-PTDSS1 »
Uniprot-PTDSS1 »
Biogrid-PTDSS1 »
ProteomicsDB-PTDSS1 »

Tumorportal-PTDSS1 »
COSMIC-PTDSS1 »
GenomeRNAi-PTDSS1 »
Genecards-PTDSS1


Protein-protein Interactions for PTDSS1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP2A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ERBB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PLK4 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015


Protein Domains in PTDSS1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PSS IPR004277 0


Protein complexes (CORUM database) featuring PTDSS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PTDSS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0016740 transferase activity Database 0.07
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_161 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS 0 0
Category members Pathway Pathway_276 KEGG_GLYCEROPHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0006659 phosphatidylserine biosynthetic process Database 0
Category members GO Category GO:0046474 glycerophospholipid biosynthetic process Database 0


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