bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: PRPS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRPS1 0 -3.351 0.970 -0.530
PRPS1 0 -3.351 0.970 -0.530 -1.674 -0.947 0.360 0.296

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PRPS1 Ubiquitylation K212 -0.466 -0.920 _M(ox)VLVGDVK(gl)DR_
PRPS1 Ubiquitylation K176 -0.856 -1.398 _NCTIVSPDAGGAK(gl)R_
PRPS1 Ubiquitylation K18 -0.554 _IFSGSSHQDLSQK(gl)IADR_
PRPS1 Ubiquitylation K282 -1.739 _INNACFEAVVVTNTIPQEDKMK(gl)_

Background Information for PRPS1:


Pubmed-PRPS1 »
Uniprot-PRPS1 »
Biogrid-PRPS1 »
ProteomicsDB-PRPS1 »

Tumorportal-PRPS1 »
COSMIC-PRPS1 »
GenomeRNAi-PRPS1 »
Genecards-PRPS1


Protein-protein Interactions for PRPS1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PRPS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait UFL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PRPS1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PRTase-like IPR029057 0.32
Category members Rib-P_diPkinase IPR005946 0.2
Category members PRibTrfase_dom IPR000836 0.08


Protein complexes (CORUM database) featuring PRPS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PRPS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0002189 ribose phosphate diphosphokinase complex Database 0.48
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0019693 ribose phosphate metabolic process Database 0.33
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members GO Category GO:0034418 urate biosynthetic process Database 0.29
Category members GO Category GO:0043531 ADP binding Database 0.27
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0004749 ribose phosphate diphosphokinase activity Database 0.2
Category members GO Category GO:0016208 AMP binding Database 0.2
Category members GO Category GO:0019003 GDP binding Database 0.18
Category members GO Category GO:0009165 nucleotide biosynthetic process Database 0.17
Category members GO Category GO:0046101 hypoxanthine biosynthetic process Database 0.13
Category members GO Category GO:0006144 purine nucleobase metabolic process Database 0.11
Category members Pathway Pathway_51 KEGG_PENTOSE_PHOSPHATE_PATHWAY 0 0.11
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process Database 0.07
Category members GO Category GO:0031100 organ regeneration Database 0.01
Category members Disease phenotype X-linked_nonsyndromic_sensorineural_deafness_type_DFN X-linked nonsyndromic sensorineural deafness type DFN Database 0
Category members GO Category GO:0000287 magnesium ion binding Database 0
Category members GO Category GO:0006164 purine nucleotide biosynthetic process Database 0
Category members GO Category GO:0006167 AMP biosynthetic process Database 0
Category members GO Category GO:0006221 pyrimidine nucleotide biosynthetic process Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0009116 nucleoside metabolic process Database 0
Category members GO Category GO:0009156 ribonucleoside monophosphate biosynthetic process Database 0
Category members GO Category GO:0030246 carbohydrate binding Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0


.

© Copyright Svejstrup Laboratory 2015