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Query: PREPL

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PREPL 0 1.331 -1.590 2.350

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PREPL Ubiquitylation K661 -1.019 _GIVSYTEKLK(gl)_

Background Information for PREPL:


Pubmed-PREPL »
Uniprot-PREPL »
Biogrid-PREPL »
ProteomicsDB-PREPL »

Tumorportal-PREPL »
COSMIC-PREPL »
GenomeRNAi-PREPL »
Genecards-PREPL


Protein-protein Interactions for PREPL
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACAA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARHGAP36 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C4orf26 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIG3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDHX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RGS4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDHB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YBEY Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PREPL
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peptidase_S9A IPR002470 0.08
Category members Pept_S9A_N IPR023302 0.08
Category members Peptidase_S9 IPR001375 0
Category members AB_hydrolase IPR029058 0


Protein complexes (CORUM database) featuring PREPL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PREPL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members Disease phenotype Atypical_hypotonia_-_cystinuria_syndrome Atypical hypotonia - cystinuria syndrome Database 0.26
Category members Disease phenotype 2p21_microdeletion_syndrome 2p21 microdeletion syndrome Database 0.23
Category members GO Category GO:0070008 serine-type exopeptidase activity Database 0.13
Category members Disease phenotype 2p21_microdeletion_syndrome_without_cystinuria 2p21 microdeletion syndrome without cystinuria Database 0.08
Category members Disease phenotype hypotonia-cystinuria_syndrome hypotonia-cystinuria syndrome Database 0.08
Category members Disease phenotype Hypotonia_-_cystinuria_syndrome Hypotonia - cystinuria syndrome Database 0.08
Category members GO Category GO:0004252 serine-type endopeptidase activity Database 0.05
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0008236 serine-type peptidase activity Database 0


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