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Query: PRC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRC1 0 0.110 1.140 -0.600 0.126 -0.141 0.522 -0.479 0.317

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PRC1 Ubiquitylation K178 -0.491 0.434 _REEFVSIK(gl)R_
PRC1 Phosphorylation S513 -0.319 _PIFGGTVYHS(ph)PVSR_
PRC1 Ubiquitylation K390 -0.497 _GGNLLKEEK(gl)QR_

Background Information for PRC1:


Pubmed-PRC1 »
Uniprot-PRC1 »
Biogrid-PRC1 »
ProteomicsDB-PRC1 »

Tumorportal-PRC1 »
COSMIC-PRC1 »
GenomeRNAi-PRC1 »
Genecards-PRC1


Protein-protein Interactions for PRC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EXOSC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait IFI30 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LTBR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PRC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members MAP65_Ase1_PRC1 IPR007145 0


Protein complexes (CORUM database) featuring PRC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PRC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0005876 spindle microtubule Database 0.68
Category members GO Category GO:0000226 microtubule cytoskeleton organization Database 0.5
Category members GO Category GO:0005819 spindle Database 0.41
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0000922 spindle pole Database 0.35
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members Pathway Pathway_1028 PID_PLK1_PATHWAY 0 0.16
Category members GO Category GO:0000910 cytokinesis Database 0.15
Category members GO Category GO:0000022 mitotic spindle elongation Database 0


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