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Query: PPP6R3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPP6R3 0 0.108 -0.570 0.210 0.279 -0.964 -0.344 0.049

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PPP6R3 Phosphorylation S617 0.720 0.380 _IQQFDDGGS(ph)DEEDIWEEK_
PPP6R3 Phosphorylation T631 -0.147 0.246 _HIAFT(ph)PESQR_
PPP6R3 Ubiquitylation K509 0.190 -0.412 _WETFCTSSLGETNK(gl)R_

Background Information for PPP6R3:


Pubmed-PPP6R3 »
Uniprot-PPP6R3 »
Biogrid-PPP6R3 »
ProteomicsDB-PPP6R3 »

Tumorportal-PPP6R3 »
COSMIC-PPP6R3 »
GenomeRNAi-PPP6R3 »
Genecards-PPP6R3


Protein-protein Interactions for PPP6R3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANKRD28 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP6C Cat. description Hein, Mann, Cell 2015
Category members IP bait ANKRD44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AURKA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRMT2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PPP6R3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members SAPS IPR007587 0.6


Protein complexes (CORUM database) featuring PPP6R3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3075 UTX-MLL2/3 complex Database 0


Categories featuring PPP6R3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0019903 protein phosphatase binding Database 0.33
Category members GO Category GO:0043666 regulation of phosphoprotein phosphatase activity Database 0


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