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Query: PIEZO1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PIEZO1 0 0.214 -0.330 0.310

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PIEZO1 Phosphorylation S1646 0.909 0.936 _TAS(ph)ELLLDRR_
PIEZO1 Phosphorylation S1621 0.613 0.280 _SGS(ph)EEAVTDPGER_
PIEZO1 Phosphorylation S1619 0.691 0.120 _S(ph)GSEEAVTDPGER_
PIEZO1 Ubiquitylation K113 -1.620 -0.320 _LDLK(gl)DIPNAIR_
PIEZO1 Ubiquitylation K1351 -0.505 _SLAQLK(gl)R_
PIEZO1 Ubiquitylation K1345 -0.652 _IEEK(gl)SLAQLKR_
PIEZO1 Phosphorylation S1391 -0.722 -0.897 _DPGLEPGPDS(ph)PGGSSPPR_
PIEZO1 Phosphorylation S1396 -0.765 _DPGLEPGPDSPGGSS(ph)PPR_

Background Information for PIEZO1:


Pubmed-PIEZO1 »
Uniprot-PIEZO1 »
Biogrid-PIEZO1 »
ProteomicsDB-PIEZO1 »

Tumorportal-PIEZO1 »
COSMIC-PIEZO1 »
GenomeRNAi-PIEZO1 »
Genecards-PIEZO1


Protein-protein Interactions for PIEZO1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GJB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB7A Cat. description Hein, Mann, Cell 2015
Category members IP bait VAPA Cat. description Hein, Mann, Cell 2015


Protein Domains in PIEZO1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Piezo IPR027272 0


Protein complexes (CORUM database) featuring PIEZO1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3


Categories featuring PIEZO1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane Database 0.05
Category members GO Category GO:0042391 regulation of membrane potential Database 0
Category members GO Category GO:0005261 cation channel activity Database 0
Category members GO Category GO:0006812 cation transport Database 0
Category members GO Category GO:0008381 mechanically-gated ion channel activity Database 0
Category members GO Category GO:0033625 positive regulation of integrin activation Database 0
Category members GO Category GO:0033634 positive regulation of cell-cell adhesion mediated by integrin Database 0
Category members GO Category GO:0050982 detection of mechanical stimulus Database 0


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