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Query: PHC3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PHC3 1 3.811 -1.660 2.820
PHC3 1 3.811 -1.660 2.820 0.376

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PHC3 Phosphorylation S263 0.297 0.318 _ISQRDPS(ph)PESNK_
PHC3 Phosphorylation T764 0.158 _HADNSSDT(ph)EMEDMIAEETLEEMDSELLK_
PHC3 Phosphorylation S762 0.035 _HADNSS(ph)DTEMEDMIAEETLEEMDSELLK_
PHC3 Phosphorylation S761 0.019 _HADNS(ph)SDTEMEDMIAEETLEEMDSELLK_
PHC3 Phosphorylation S842 -0.278 _GRRPS(ph)GPDGAAR_
PHC3 Phosphorylation S315 -0.458 _HQQIPLHS(ph)PPSK_
PHC3 Phosphorylation T609 -0.358 -0.757 _MDRT(ph)PPPPTLS(ph)PAAITVGR_
PHC3 Phosphorylation S616 -0.738 -0.757 _MDRT(ph)PPPPTLS(ph)PAAITVGR_

Background Information for PHC3:





Protein-protein Interactions for PHC3

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CBX4 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX7 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX8 Cat. description Hein, Mann, Cell 2015
Category members IP bait MLLT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RING1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDI1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCGF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PHC3

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FCS IPR012313 0.31
Category members SAM IPR001660 0
Category members Pointed_dom IPR003118 0
Category members SAM_2 IPR011510 0
Category members SAM/pointed IPR013761 0
Category members SAM_type1 IPR021129 0


Protein complexes (CORUM database) featuring PHC3

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 116 Polycomb repressive complex 1 (PRC1, hPRC-H) Database 1.56
Category members Corum 115 Polycomb repressive complex 1 (PRC1, hPRC-H) Database 1.28


Categories featuring PHC3

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0031519 PcG protein complex Database 0.62
Category members GO Category GO:0035102 PRC1 complex Database 0.62
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18


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