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Query: PGRMC2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PGRMC2 0 3.292 1.140 -0.850 -0.150 -0.121
PGRMC2 0 3.292 1.140 -0.850 -0.063 -0.102 -0.106 0.220 -0.024

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PGRMC2 Ubiquitylation K132 -0.005 1.337 _VFDVTK(gl)GSK_
PGRMC2 Ubiquitylation K135 -0.732 1.337 _GSK(gl)FYGPAGPYGIFAGR_
PGRMC2 Phosphorylation S154 0.383 _EALKDEYDDLSDLTAAQQETLS(ph)DWESQFTFK_
PGRMC2 Phosphorylation T211 1.469 0.350 _LLKPGEEPSEYT(ph)DEEDTK_
PGRMC2 Ubiquitylation K193 -0.975 0.231 _EK(gl)YDYVGR_
PGRMC2 Phosphorylation S90 0.274 0.160 _RGLGAGAGAGEES(ph)PATSLPR_
PGRMC2 Ubiquitylation K102 0.115 0.152 _VFDVTK(gl)GR_
PGRMC2 Phosphorylation Y180 -0.062 _LLKEGEEPTVY(ph)SDEEEPKDESAR_
PGRMC2 Phosphorylation S181 -0.030 -0.212 _EGEEPTVYS(ph)DEEEPKDESAR_
PGRMC2 Phosphorylation T178 -0.196 -0.388 _EGEEPT(ph)VYSDEEEPKDESAR_
PGRMC2 Ubiquitylation K105 -1.237 -1.007 _K(gl)FYGPEGPYGVFAGR_
PGRMC2 Phosphorylation S57 -1.069 -1.271 _GDQPAASGDS(ph)DDDEPPPLPR_
PGRMC2 Phosphorylation S54 -0.398 -1.547 _GDQPAAS(ph)GDSDDDEPPPLPR_
PGRMC2 Ubiquitylation K96 -0.670 _ILMAINGK(gl)VFDVTK_
PGRMC2 Ubiquitylation K172 -1.786 _LLK(gl)EGEEPTVYSDEEEPKDESAR_

Background Information for PGRMC2:





Protein-protein Interactions for PGRMC2

Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in PGRMC2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cyt_B5-like_heme/steroid-bd IPR001199 1.28


Protein complexes (CORUM database) featuring PGRMC2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PGRMC2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0020037 heme binding Database 0.04
Category members GO Category GO:0003707 steroid hormone receptor activity Database 0
Category members GO Category GO:0005496 steroid binding Database 0
Category members GO Category GO:0043401 steroid hormone mediated signaling pathway Database 0


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