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Query: PFDN6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PFDN6 0 2.405 0.260 0.480

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PFDN6 Ubiquitylation K88 0.577 1.348 _RLDYITAEIK(gl)R_
PFDN6 Ubiquitylation K15 0.315 0.721 _LQGEVEK(gl)YQQLQK_
PFDN6 Ubiquitylation K25 0.072 0.095 _DLSK(gl)SMSGR_
PFDN6 Ubiquitylation K8 -0.099 _K(gl)LQGEVEK_
PFDN6 Ubiquitylation K66 -1.103 _LLGPVLVK(gl)QELGEAR_

Background Information for PFDN6:


Pubmed-PFDN6 »
Uniprot-PFDN6 »
Biogrid-PFDN6 »
ProteomicsDB-PFDN6 »

Tumorportal-PFDN6 »
COSMIC-PFDN6 »
GenomeRNAi-PFDN6 »
Genecards-PFDN6


Protein-protein Interactions for PFDN6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ISY1;RAB43 Cat. description Hein, Mann, Cell 2015
Category members IP bait PFDN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR3E Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait VBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait WDR61 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCAF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PFDN4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UXT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PFDN6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PFD_beta-like IPR002777 0.31
Category members Prefoldin IPR009053 0


Protein complexes (CORUM database) featuring PFDN6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 112 Prefoldin complex Database 0.27
Category members Corum 33 Prefoldin Database 0.27


Categories featuring PFDN6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members GO Category GO:0051087 chaperone binding Database 1.69
Category members Pathway Pathway_742 REACTOME_PROTEIN_FOLDING 0 0.9
Category members GO Category GO:0051084 'de novo' posttranslational protein folding Database 0.63
Category members Pathway Pathway_1288 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC 0 0.4
Category members GO Category GO:0051131 chaperone-mediated protein complex assembly Database 0.24
Category members GO Category GO:0016272 prefoldin complex Database 0.15


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