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Query: PDHX

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PDHX 0 2.775 -0.260 -0.330 1.199 0.001 -0.468 1.487 0.557

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for PDHX:





Protein-protein Interactions for PDHX

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HDAC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait STAT5A Cat. description Hein, Mann, Cell 2015
Category members IP bait STAT5B Cat. description Hein, Mann, Cell 2015
Category members IP bait DLD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDHB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDHX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PDHX

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members 2-oxoacid_DH_actylTfrase IPR001078 0.32
Category members E3-bd IPR004167 0.11
Category members Biotin_lipoyl IPR000089 0.04
Category members Single_hybrid_motif IPR011053 0.02


Protein complexes (CORUM database) featuring PDHX

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PDHX

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_10 REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE 0 1.76
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0016746 transferase activity, transferring acyl groups Database 0.17
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members Pathway Pathway_14 REACTOME_PYRUVATE_METABOLISM 0 0.05
Category members Pathway Pathway_13 REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 0 0.04
Category members GO Category GO:0006090 pyruvate metabolic process Database 0.04
Category members Pathway Pathway_15 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX 0 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate Database 0


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