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Query: PDE4DIP

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PDE4DIP 0 0.680 -0.640 0.350

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PDE4DIP Ubiquitylation K86 0.330 _LLLEK(gl)DRLK_

Background Information for PDE4DIP:


Pubmed-PDE4DIP »
Uniprot-PDE4DIP »
Biogrid-PDE4DIP »
ProteomicsDB-PDE4DIP »

Tumorportal-PDE4DIP »
COSMIC-PDE4DIP »
GenomeRNAi-PDE4DIP »
Genecards-PDE4DIP


Protein-protein Interactions for PDE4DIP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK5RAP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNLL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKACB Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKAR2A Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKAR2B Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CSNK1D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CSNK1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAPRE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDE4DIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCCPDH Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PDE4DIP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26


Protein complexes (CORUM database) featuring PDE4DIP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PDE4DIP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0043623 cellular protein complex assembly Database 0.45
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0030016 myofibril Database 0


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