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Query: PDE12

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PDE12 0 -0.102 0.110 0.030 0.029 -0.147 -0.122

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PDE12 Ubiquitylation K427 -0.158 0.382 _LVLYPSAQEK(gl)VLQR_
PDE12 Ubiquitylation K84 0.125 0.028 _IATNALK(gl)GHAK_
PDE12 Phosphorylation S219 -1.067 _EAKPGAAEPEVGVPSSLSPS(ph)SPSSSWTETDVEER_
PDE12 Ubiquitylation K377 0.823 _IK(gl)QHEGLATFYR_

Background Information for PDE12:


Pubmed-PDE12 »
Uniprot-PDE12 »
Biogrid-PDE12 »
ProteomicsDB-PDE12 »

Tumorportal-PDE12 »
COSMIC-PDE12 »
GenomeRNAi-PDE12 »
Genecards-PDE12


Protein-protein Interactions for PDE12
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG6;BAT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait RHOA Cat. description Hein, Mann, Cell 2015
Category members IP bait SGTB Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait VWA9 Cat. description Hein, Mann, Cell 2015


Protein Domains in PDE12
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Endo/exonuclease/phosphatase IPR005135 0


Protein complexes (CORUM database) featuring PDE12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PDE12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0004535 poly(A)-specific ribonuclease activity Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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