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Query: PDAP1

This is a cancer-associated gene according to the Broad cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PDAP1 0 2.420 1.130 -0.920

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PDAP1 Phosphorylation S176 0.693 1.377 _MQS(ph)LSLNK_
PDAP1 Phosphorylation S60 0.041 1.166 _SLDS(ph)DES(ph)EDEEDDYQQK_
PDAP1 Phosphorylation S63 -0.264 0.815 _SLDSDES(ph)EDEEDDYQQK_
PDAP1 Phosphorylation S57 0.612 0.628 _S(ph)LDSDES(ph)EDEEDDYQQK_
PDAP1 Phosphorylation S19 -0.206 -0.057 _QYTS(ph)PEEIDAQLQAEK_
PDAP1 Phosphorylation T18 0.012 -0.726 _QYT(ph)SPEEIDAQLQAEK_
PDAP1 Ubiquitylation K31 -0.628 _QYTSPEEIDAQLQAEK(gl)QK_
PDAP1 Ubiquitylation K132 0.350 _M(ox)HLAGK(gl)TEQAK_

Background Information for PDAP1:





Protein-protein Interactions for PDAP1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015


Protein Domains in PDAP1

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring PDAP1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PDAP1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Human mutations Broad_cancer_genes Broad cancer genes (Lawrence et al., 2014) literature 1.14
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0007165 signal transduction Database 0


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