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Query: PAPSS2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PAPSS2 0 -0.009 0.720 -0.260

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PAPSS2 Ubiquitylation K603 -0.009 _EGENPPDGFMAPK(gl)AWK_

Background Information for PAPSS2:





Protein-protein Interactions for PAPSS2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PAPSS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAPSS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PAPSS2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Sulphate_adenylyltransferase IPR002650 0
Category members APS_kinase IPR002891 0
Category members PUA-like_domain IPR015947 0
Category members Sulfurylase_cat_dom IPR024951 0


Protein complexes (CORUM database) featuring PAPSS2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PAPSS2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0030203 glycosaminoglycan metabolic process Database 1.44
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members Pathway Pathway_181 KEGG_SULFUR_METABOLISM 0 0
Category members Pathway Pathway_180 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES 0 0
Category members Pathway Pathway_299 KEGG_SELENOAMINO_ACID_METABOLISM 0 0
Category members Pathway Pathway_82 REACTOME_PHASE_II_CONJUGATION 0 0
Category members Pathway Pathway_85 REACTOME_BIOLOGICAL_OXIDATIONS 0 0
Category members GO Category GO:0000103 sulfate assimilation Database 0
Category members GO Category GO:0001501 skeletal system development Database 0
Category members GO Category GO:0004020 adenylylsulfate kinase activity Database 0
Category members GO Category GO:0004781 sulfate adenylyltransferase (ATP) activity Database 0
Category members GO Category GO:0006805 xenobiotic metabolic process Database 0
Category members GO Category GO:0016779 nucleotidyltransferase activity Database 0
Category members GO Category GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process Database 0
Category members GO Category GO:0050428 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process Database 0
Category members GO Category GO:0060348 bone development Database 0


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