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Query: PAFAH1B2

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PAFAH1B2 2 5.670 0.860 -0.860 0.330 0.522

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PAFAH1B2 Phosphorylation S2 2.361 2.457 _(ac)S(ph)QGDSNPAAIPHAAEDIQGDDRWMSQHNR_

Background Information for PAFAH1B2:


Pubmed-PAFAH1B2 »
Uniprot-PAFAH1B2 »
Biogrid-PAFAH1B2 »
ProteomicsDB-PAFAH1B2 »

Tumorportal-PAFAH1B2 »
COSMIC-PAFAH1B2 »
GenomeRNAi-PAFAH1B2 »
Genecards-PAFAH1B2


Protein-protein Interactions for PAFAH1B2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PAFAH1B1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAFAH1B2 Cat. description Hein, Mann, Cell 2015


Protein Domains in PAFAH1B2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Lipase_GDSL IPR001087 0


Protein complexes (CORUM database) featuring PAFAH1B2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PAFAH1B2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members Pathway Pathway_729 PID_LIS1_PATHWAY 0 1.41
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity Database 0.4
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0016239 positive regulation of macroautophagy Database 0.09
Category members Pathway Pathway_497 KEGG_ETHER_LIPID_METABOLISM 0 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0007283 spermatogenesis Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0016042 lipid catabolic process Database 0
Category members GO Category GO:0016788 hydrolase activity, acting on ester bonds Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0


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