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bioLOGIC Data

Query: OSBPL3

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
OSBPL3	1	4.717	0.890	-0.840	2.244				0.436

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
OSBPL3	Phosphorylation	S437	0.653	1.111	_ALVHQLS(ph)NESR_
OSBPL3	Phosphorylation	S251	0.321	0.564	_TYS(ph)APAINAIQGGSFESPK_
OSBPL3	Phosphorylation	S303	-0.008	0.146	_LHS(ph)SNPNLSTLDFGEEK_
OSBPL3	Phosphorylation	S304	0.191	0.104	_LHSS(ph)NPNLSTLDFGEEK_
OSBPL3	Ubiquitylation	K55	0.273		_GEMNYTQEPPVQK(gl)GFLLK_
OSBPL3	Phosphorylation	T249	-0.465		_T(ph)YSAPAINAIQGGSFESPK_

Background Information for OSBPL3:

Pubmed-OSBPL3 »

Uniprot-OSBPL3 »

Biogrid-OSBPL3 »

ProteomicsDB-OSBPL3 »

Tumorportal-OSBPL3 »

COSMIC-OSBPL3 »

GenomeRNAi-OSBPL3 »

Genecards-OSBPL3

Protein-protein Interactions for OSBPL3

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait JUNB	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait KTN1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MMGT1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait RPL35	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SMC1A	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait TMED2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait VAPA	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait ACTR3B	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ARRDC1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait AURKA	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait C8orf41	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CPNE2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait GLTSCR2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait HDAC11	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait HIF1AN	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ILVBL	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait JPH4	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait PRICKLE3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TRAF1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TSPYL1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait VAPA	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait VAPB	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZFPL1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in OSBPL3

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	PH_domain	IPR001849	0.14
Category members	Oxysterol-bd	IPR000648	0

Protein complexes (CORUM database) featuring OSBPL3

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring OSBPL3

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005829	cytosol	Database	INF
Category members	GO Category	GO:0031965	nuclear membrane	Database	2.59
Category members	GO Category	GO:0005886	plasma membrane	Database	1.21
Category members	GO Category	GO:0015485	cholesterol binding	Database	0.04
Category members	GO Category	GO:0006869	lipid transport	Database	0