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Query: OSBP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
OSBP 2 3.933 -0.940 1.310 -0.825 -0.605

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
OSBP Phosphorylation S379 1.905 2.129 _TGS(ph)NISGASSDISLDEQYK_
OSBP Phosphorylation T377 1.867 1.031 _T(ph)GSNIS(ph)GASSDISLDEQYK_
OSBP Phosphorylation S382 0.925 0.732 _T(ph)GSNIS(ph)GASSDISLDEQYK_
OSBP Phosphorylation S351 -0.378 -0.478 _GDM(ox)S(ph)DEDDENEFFDAPEIITM(ox)PENLGHK_
OSBP Ubiquitylation K246 -1.328 _SLSELESLK(gl)LPAESNEK_
OSBP Ubiquitylation K429 1.347 _NCIGK(gl)ELSK_

Background Information for OSBP:


Pubmed-OSBP »
Uniprot-OSBP »
Biogrid-OSBP »
ProteomicsDB-OSBP »

Tumorportal-OSBP »
COSMIC-OSBP »
GenomeRNAi-OSBP »
Genecards-OSBP


Protein-protein Interactions for OSBP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait VAPA Cat. description Hein, Mann, Cell 2015
Category members IP bait BTN2A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BTNL8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FKBP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRTM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHB16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGA5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAPA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNRF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in OSBP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PH_domain IPR001849 0.14
Category members Oxysterol-bd IPR000648 0


Protein complexes (CORUM database) featuring OSBP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring OSBP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_128 REACTOME_SPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_498 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0006869 lipid transport Database 0
Category members GO Category GO:0008142 oxysterol binding Database 0


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