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Query: ORMDL3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ORMDL3 0 -0.961 0.830 -0.800
ORMDL3 0 -0.961 0.830 -0.800 -0.585

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ORMDL3 Ubiquitylation K152 0.218 _VFGINK(gl)Y_
ORMDL3 Ubiquitylation K152 -0.594 0.060 _IFGINK(gl)Y_
ORMDL3 Ubiquitylation K79 -1.231 -0.288 _GTPFETPDQGK(gl)AR_

Background Information for ORMDL3:


Pubmed-ORMDL3 »
Uniprot-ORMDL3 »
Biogrid-ORMDL3 »
ProteomicsDB-ORMDL3 »

Tumorportal-ORMDL3 »
COSMIC-ORMDL3 »
GenomeRNAi-ORMDL3 »
Genecards-ORMDL3


Protein-protein Interactions for ORMDL3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ORMDL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC22A9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC2A12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ORMDL3
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring ORMDL3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ORMDL3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members Disease phenotype ASTHMA_SUSCEPTIBILITY_TO ASTHMA SUSCEPTIBILITY TO Database 0.04
Category members GO Category GO:0006672 ceramide metabolic process Database 0


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