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Query: OGT

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
OGT 0 -0.127 1.490 -0.570 -0.592 -0.437 0.134 -0.210

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
OGT Ubiquitylation K550 0.459 0.519 _DLK(gl)LSDGR_
OGT Ubiquitylation K991 0.231 _LGTDLEYLK(gl)K_
OGT Ubiquitylation K755 -0.071 _AFLDSLPDVKIVK(gl)_
OGT Ubiquitylation K752 -0.448 -0.267 _AFLDSLPDVK(gl)IVK_
OGT Ubiquitylation K16 -0.519 -0.569 _(ac)ASSVGNVADSTEPTK(gl)R_
OGT Ubiquitylation K168 0.402 _SDLGNLLK(gl)ALGR_
OGT Ubiquitylation K1010 0.122 _ISSPLFNTK(gl)QYTMELER_

Background Information for OGT:


Pubmed-OGT »
Uniprot-OGT »
Biogrid-OGT »
ProteomicsDB-OGT »

Tumorportal-OGT »
COSMIC-OGT »
GenomeRNAi-OGT »
Genecards-OGT


Protein-protein Interactions for OGT
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C20orf43;RTFDC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CXXC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DENND6A Cat. description Hein, Mann, Cell 2015
Category members IP bait HUWE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ITGA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait KAT8 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF5B Cat. description Hein, Mann, Cell 2015
Category members IP bait LGALS3BP Cat. description Hein, Mann, Cell 2015
Category members IP bait MAX Cat. description Hein, Mann, Cell 2015
Category members IP bait MCM3 Cat. description Hein, Mann, Cell 2015
Category members IP bait NDEL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C1orf51 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAMK2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CREB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDAH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HCFC1R1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HCFC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THAP11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THAP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRAK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in OGT
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TPR_1 IPR001440 1.39
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93
Category members TPR_2 IPR013105 0.45
Category members TPR-4 IPR011717 0


Protein complexes (CORUM database) featuring OGT
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2721 HCF-1 complex Database 2.08
Category members Corum 177 OGT-TRAK1-TRAK2 complex Database 0


Categories featuring OGT
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0051571 positive regulation of histone H3-K4 methylation Database 0.99
Category members GO Category GO:0048015 phosphatidylinositol-mediated signaling Database 0.98
Category members GO Category GO:0043085 positive regulation of catalytic activity Database 0.78
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0043981 histone H4-K5 acetylation Database 0.43
Category members GO Category GO:0043982 histone H4-K8 acetylation Database 0.43
Category members GO Category GO:0006493 protein O-linked glycosylation Database 0.32
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0070688 MLL5-L complex Database 0.25
Category members GO Category GO:0000123 histone acetyltransferase complex Database 0.15
Category members GO Category GO:0008047 enzyme activator activity Database 0.15
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0043984 histone H4-K16 acetylation Database 0.07
Category members GO Category GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding Database 0.04
Category members GO Category GO:0043995 histone acetyltransferase activity (H4-K5 specific) Database 0.04
Category members GO Category GO:0043996 histone acetyltransferase activity (H4-K8 specific) Database 0.04
Category members GO Category GO:0046626 regulation of insulin receptor signaling pathway Database 0.04
Category members GO Category GO:0046972 histone acetyltransferase activity (H4-K16 specific) Database 0.04
Category members GO Category GO:0030854 positive regulation of granulocyte differentiation Database 0.04
Category members GO Category GO:0006110 regulation of glycolysis Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007584 response to nutrient Database 0
Category members GO Category GO:0008375 acetylglucosaminyltransferase activity Database 0
Category members GO Category GO:0016262 protein N-acetylglucosaminyltransferase activity Database 0
Category members GO Category GO:0032868 response to insulin Database 0
Category members GO Category GO:0035020 regulation of Rac protein signal transduction Database 0
Category members GO Category GO:0045862 positive regulation of proteolysis Database 0
Category members GO Category GO:0071300 cellular response to retinoic acid Database 0


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