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Query: NR3C2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NR3C2 0 1.110 -0.330 -0.270

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NR3C2 Phosphorylation S361 0.013 _DVVPS(ph)PDTQEK_
NR3C2 Ubiquitylation K779 -0.048 _LAGK(gl)QMIQVVK_
NR3C2 Phosphorylation S250 -0.427 _SHS(ph)PAHASNVGSPLSSPLSSM(ox)K_
NR3C2 Phosphorylation S129 1.415 _DADYSYEQQNQQGSM(ox)S(ph)PAK_

Background Information for NR3C2:


Pubmed-NR3C2 »
Uniprot-NR3C2 »
Biogrid-NR3C2 »
ProteomicsDB-NR3C2 »

Tumorportal-NR3C2 »
COSMIC-NR3C2 »
GenomeRNAi-NR3C2 »
Genecards-NR3C2


Protein-protein Interactions for NR3C2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C9orf41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NR3C2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Nucl_hrmn_rcpt_lig-bd_core IPR000536 0
Category members Znf_hrmn_rcpt IPR001628 0
Category members Nucl_hormone_rcpt_ligand-bd IPR008946 0


Protein complexes (CORUM database) featuring NR3C2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 786 MR-UBC9-SRC1 complex Database 0.11
Category members Corum 3634 NR3C2-UBC9-SRC-1 complex Database 0


Categories featuring NR3C2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members GO Category GO:0007588 excretion Database 0.08
Category members Pathway Pathway_176 KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION 0 0
Category members Pathway Pathway_929 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY 0 0
Category members GO Category GO:0003707 steroid hormone receptor activity Database 0
Category members GO Category GO:0005496 steroid binding Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006883 cellular sodium ion homeostasis Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0043401 steroid hormone mediated signaling pathway Database 0


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