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Query: NOSIP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NOSIP 0 -2.803 -0.770 0.280 -0.283 -0.597 -1.070

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NOSIP Phosphorylation S138 -0.588 -0.426 _ALSGTS(ph)PDDVQPGPSVGPPSK_
NOSIP Phosphorylation T168 -1.427 _VLPSFWIPSLT(ph)PEAK_
NOSIP Phosphorylation S135 -0.306 _ALS(ph)GTSPDDVQPGPSVGPPSK_
NOSIP Ubiquitylation K175 -0.401 _ATK(gl)LEKPSR_

Background Information for NOSIP:





Protein-protein Interactions for NOSIP

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait NEU2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NOSIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLL Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NOSIP

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Rtf2_RING-finger IPR027799 0.13


Protein complexes (CORUM database) featuring NOSIP

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NOSIP

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_438 REACTOME_ENOS_ACTIVATION_AND_REGULATION 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0043086 negative regulation of catalytic activity Database 0
Category members GO Category GO:0046209 nitric oxide metabolic process Database 0
Category members GO Category GO:0050999 regulation of nitric-oxide synthase activity Database 0
Category members GO Category GO:0051001 negative regulation of nitric-oxide synthase activity Database 0


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