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Query: NEDD8-MDP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NEDD8-MDP1 1 4.390
NEDD8-MDP1 1 4.390 1.506 1.366 -0.201 -0.221
NEDD8-MDP1 1 4.390 0.333

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NEDD8-MDP1 Ubiquitylation K48 0.753 0.302 _LIYSGK(gl)QMNDEK_
NEDD8-MDP1 Ubiquitylation K54 1.305 0.078 _QMNDEK(gl)TAADYK_
NEDD8-MDP1 Ubiquitylation K11 0.414 _TLTGK(gl)EIEIDIEPTDKVER_
NEDD8-MDP1 Ubiquitylation K22 0.364 _EIEIDIEPTDK(gl)VER_
NEDD8-MDP1 Ubiquitylation K27 0.033 _IK(gl)ERVEEK_

Background Information for NEDD8-MDP1:


Pubmed-NEDD8-MDP1 »
Uniprot-NEDD8-MDP1 »
Biogrid-NEDD8-MDP1 »
ProteomicsDB-NEDD8-MDP1 »

Tumorportal-NEDD8-MDP1 »
COSMIC-NEDD8-MDP1 »
GenomeRNAi-NEDD8-MDP1 »
Genecards-NEDD8-MDP1


Protein-protein Interactions for NEDD8-MDP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SLC25A32 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPATA6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NEDD8-MDP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Rad60/SUMO_like IPR022617 1.93
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members Ubiquitin-like IPR000626 1.61
Category members Ubiquitin IPR019956 0.87
Category members HAD-like_dom IPR023214 0


Protein complexes (CORUM database) featuring NEDD8-MDP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NEDD8-MDP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0008104 protein localization Database 0.5
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0045116 protein neddylation Database 0.1
Category members GO Category GO:0014070 response to organic cyclic compound Database 0
Category members GO Category GO:0016791 phosphatase activity Database 0


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