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Query: NARS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NARS 0 2.332 -1.280 2.000 -1.057 0.562 0.469

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NARS Ubiquitylation K244 -0.207 _GENMSK(gl)ILK_
NARS Ubiquitylation K104 -0.855 -0.763 _ITIK(gl)NDPSLPEPK_
NARS Ubiquitylation K60 0.565 _WNVISK(gl)SQLK_
NARS Ubiquitylation K490 -0.157 _IFDSEEILAGYK(gl)R_

Background Information for NARS:





Protein-protein Interactions for NARS

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AMTN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf93 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX19B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DUSP19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF2E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSD3B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LILRA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRMT11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NARS

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members NA-bd_OB-fold IPR012340 4.37
Category members Asp/Asn-tRNA-synth_IIb IPR002312 0.4
Category members NA-bd_OB_tRNA IPR004365 0.35
Category members aa-tRNA-synth_II IPR006195 0.24
Category members aa-tRNA-synt_II IPR004364 0.15
Category members Asn-tRNA-ligase IPR004522 0.05


Protein complexes (CORUM database) featuring NARS

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NARS

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_201 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION 0 3.57
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_202 REACTOME_TRNA_AMINOACYLATION 0 1.34
Category members GO Category GO:0006418 tRNA aminoacylation for protein translation Database 0.91
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members Pathway Pathway_409 KEGG_AMINOACYL_TRNA_BIOSYNTHESIS 0 0.82
Category members GO Category GO:0004812 aminoacyl-tRNA ligase activity Database 0.41
Category members GO Category GO:0004816 asparagine-tRNA ligase activity Database 0.05
Category members GO Category GO:0006421 asparaginyl-tRNA aminoacylation Database 0.05


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