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Query: MYO5B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MYO5B 4 11.246 0.120 0.600 1.086 -0.115 0.036 0.805 0.500

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MYO5B Phosphorylation S401 2.552 2.428 _LSQLEEHLS(ph)QLQDNPPQEK_
MYO5B Phosphorylation S82 2.155 _KHPS(ph)SPECLVSAQK_
MYO5B Ubiquitylation K897 0.451 1.826 _ALQQVQEK(gl)EVR_
MYO5B Phosphorylation S1231 0.725 1.160 _KNS(ph)LISSLEEEVSILNR_
MYO5B Phosphorylation S1795 -0.386 1.025 _SQAPLESS(ph)LDSLGDVFLDSGR_
MYO5B Phosphorylation S1794 0.156 0.929 _SQAPLES(ph)SLDSLGDVFLDSGRK_
MYO5B Ubiquitylation K1517 0.737 0.662 _ELEVMTAK(gl)YEGAK_
MYO5B Ubiquitylation K914 -0.138 0.483 _LADDLSTLQEK(gl)MAATSK_
MYO5B Phosphorylation S1775 -0.770 0.419 _VES(ph)LESLYFTPIPAR_
MYO5B Phosphorylation T1755 -0.222 _TQPDGT(ph)SVPGEPASPISQR_
MYO5B Phosphorylation S1766 -0.247 _TQPDGTSVPGEPASPIS(ph)QR_
MYO5B Phosphorylation S1763 0.155 -0.387 _TQPDGTSVPGEPAS(ph)PISQR_
MYO5B Phosphorylation S1868 -0.414 -0.685 _LGS(ph)PDYGNSALLSLPGYRPTTR_
MYO5B Phosphorylation S175 -0.787 -0.756 _APVPSTCSSTFPEELS(ph)PPSHQAK_
MYO5B Phosphorylation T2006 -0.114 -1.359 _RVSLEPHQGPGT(ph)PESK_
MYO5B Ubiquitylation K567 1.115 _HQVEQLSSSLK(gl)QK_
MYO5B Ubiquitylation K569 1.115 _HQVEQLSSSLK(gl)QK_
MYO5B Ubiquitylation K903 0.485 _AQK(gl)LADDLSTLQEK_
MYO5B Ubiquitylation K920 -0.270 _MAATSK(gl)EVAR_
MYO5B Ubiquitylation K945 -0.207 _ELVK(gl)EPAR_
MYO5B Ubiquitylation K1144 -0.145 _LEQQCQK(gl)QQEQADSLER_
MYO5B Ubiquitylation K1336 0.352 _AEELGQELK(gl)AWQEK_
MYO5B Ubiquitylation K1481 0.696 _EK(gl)YVQELAAVR_
MYO5B Ubiquitylation K1579 0.874 _LK(gl)AVQAQGGESQQEAQR_
MYO5B Ubiquitylation K1671 1.528 _LGHELQQAGLK(gl)TK_
MYO5B Ubiquitylation K1705 0.380 _DLGK(gl)FQVATDALK_
MYO5B Ubiquitylation K1714 1.086 _FQVATDALK(gl)SR_
MYO5B Phosphorylation S1756 0.224 _TQPDGTS(ph)VPGEPASPISQR_
MYO5B Ubiquitylation K1828 0.570 _TTQIINITMTKK(gl)_

Background Information for MYO5B:


Pubmed-MYO5B »
Uniprot-MYO5B »
Biogrid-MYO5B »
ProteomicsDB-MYO5B »

Tumorportal-MYO5B »
COSMIC-MYO5B »
GenomeRNAi-MYO5B »
Genecards-MYO5B


Protein-protein Interactions for MYO5B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait SKA3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DKK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC39 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PEX19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP6R2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MYO5B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Myosin_head_motor_dom IPR001609 0.17
Category members IQ_motif_EF-hand-BS IPR000048 0
Category members Dilute IPR002710 0
Category members Prefoldin IPR009053 0
Category members Dil_domain IPR018444 0


Protein complexes (CORUM database) featuring MYO5B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MYO5B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0016459 myosin complex Database 0.38
Category members GO Category GO:0000146 microfilament motor activity Database 0.27
Category members GO Category GO:0003774 motor activity Database 0.2
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members Pathway Pathway_242 REACTOME_AQUAPORIN_MEDIATED_TRANSPORT 0 0
Category members Pathway Pathway_248 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS 0 0
Category members GO Category GO:0006833 water transport Database 0
Category members GO Category GO:0017137 Rab GTPase binding Database 0


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