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Query: MYO1B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MYO1B 0 4.582 0.110 0.360 0.137 0.249 1.311 0.007

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MYO1B Ubiquitylation K354 1.472 _DALAK(gl)NLYSR_
MYO1B Ubiquitylation K588 -0.892 _NLQTK(gl)NPNYIR_
MYO1B Ubiquitylation K303 -0.725 _IKDK(gl)NELK_
MYO1B Ubiquitylation K972 0.034 _ALYPSSVGQPFQGAYLEINK(gl)NPK_
MYO1B Ubiquitylation K980 1.046 _LK(gl)DAIEEK_

Background Information for MYO1B:


Pubmed-MYO1B »
Uniprot-MYO1B »
Biogrid-MYO1B »
ProteomicsDB-MYO1B »

Tumorportal-MYO1B »
COSMIC-MYO1B »
GenomeRNAi-MYO1B »
Genecards-MYO1B


Protein-protein Interactions for MYO1B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO5C Cat. description Hein, Mann, Cell 2015
Category members IP bait PDLIM7 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CC Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMM50 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait AVIL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCL7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCL7C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LSP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NEXN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MYO1B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Myosin_head_motor_dom IPR001609 0.17
Category members IQ_motif_EF-hand-BS IPR000048 0
Category members Myosin_tail_2 IPR010926 0


Protein complexes (CORUM database) featuring MYO1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MYO1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0051017 actin filament bundle assembly Database 0.47
Category members GO Category GO:0016459 myosin complex Database 0.38
Category members GO Category GO:0030048 actin filament-based movement Database 0.28
Category members GO Category GO:0000146 microfilament motor activity Database 0.27
Category members GO Category GO:0003774 motor activity Database 0.2
Category members GO Category GO:0005546 phosphatidylinositol-4,5-bisphosphate binding Database 0.09
Category members GO Category GO:0030175 filopodium Database 0.05
Category members GO Category GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding Database 0.04
Category members GO Category GO:0005903 brush border Database 0


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