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Query: MYL6B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MYL6B 0 2.106 -0.400 0.430 0.873 0.361 -0.268

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MYL6B Ubiquitylation K119 -0.008 0.717 _TGDGK(gl)ILYSQCGDVMR_
MYL6B Ubiquitylation K174 -0.167 0.427 _NK(gl)DQGTYEDYVEGLR_
MYL6B Ubiquitylation K149 -0.380 -0.299 _VLGNPK(gl)SDEMNVK_
MYL6B Ubiquitylation K143 -0.749 -0.696 _ALGQNPTNAEVLK(gl)VLGNPK_

Background Information for MYL6B:


Pubmed-MYL6B »
Uniprot-MYL6B »
Biogrid-MYL6B »
ProteomicsDB-MYL6B »

Tumorportal-MYL6B »
COSMIC-MYL6B »
GenomeRNAi-MYL6B »
Genecards-MYL6B


Protein-protein Interactions for MYL6B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYL12A;MYL12B Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait PDLIM7 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPA17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MYL6B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members EF_hand_dom IPR002048 0


Protein complexes (CORUM database) featuring MYL6B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MYL6B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0016459 myosin complex Database 0.38
Category members GO Category GO:0003774 motor activity Database 0.2
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members Pathway Pathway_160 KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION 0 0.01
Category members Pathway Pathway_949 REACTOME_SMOOTH_MUSCLE_CONTRACTION 0 0
Category members Pathway Pathway_950 REACTOME_MUSCLE_CONTRACTION 0 0
Category members GO Category GO:0005859 muscle myosin complex Database 0
Category members GO Category GO:0006936 muscle contraction Database 0
Category members GO Category GO:0007519 skeletal muscle tissue development Database 0
Category members GO Category GO:0008307 structural constituent of muscle Database 0
Category members GO Category GO:0016461 unconventional myosin complex Database 0
Category members GO Category GO:0030049 muscle filament sliding Database 0


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