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Query: MTRR

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MTRR 0 -0.218 -0.340 0.000

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MTRR Ubiquitylation K434 -0.269 0.050 _LQELCSK(gl)QGAADYSR_

Background Information for MTRR:


Pubmed-MTRR »
Uniprot-MTRR »
Biogrid-MTRR »
ProteomicsDB-MTRR »

Tumorportal-MTRR »
COSMIC-MTRR »
GenomeRNAi-MTRR »
Genecards-MTRR


Protein-protein Interactions for MTRR
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATM Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK13 Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait GSK3B Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF2A Cat. description Hein, Mann, Cell 2015
Category members IP bait PTEN Cat. description Hein, Mann, Cell 2015
Category members IP bait TSNAX Cat. description Hein, Mann, Cell 2015


Protein Domains in MTRR
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Flavdoxin IPR001094 0.08
Category members Flavodoxin/NO_synth IPR008254 0.08
Category members Flavoprotein-like IPR029039 0.08
Category members OxRdtase_FAD/NAD-bd IPR001433 0
Category members Flavoprot_Pyr_Nucl_cyt_Rdtase IPR001709 0
Category members FAD-binding_1 IPR003097 0
Category members Riboflavin_synthase-like_b-brl IPR017938 0


Protein complexes (CORUM database) featuring MTRR
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MTRR
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0006767 water-soluble vitamin metabolic process Database 0.27
Category members GO Category GO:0045111 intermediate filament cytoskeleton Database 0.26
Category members GO Category GO:0006766 vitamin metabolic process Database 0.23
Category members Disease phenotype NEURAL_TUBE_DEFECTS_FOLATE-SENSITIVE NEURAL TUBE DEFECTS FOLATE-SENSITIVE Database 0.23
Category members GO Category GO:0006306 DNA methylation Database 0.22
Category members GO Category GO:0009086 methionine biosynthetic process Database 0.17
Category members GO Category GO:0000096 sulfur amino acid metabolic process Database 0.15
Category members GO Category GO:0050660 flavin adenine dinucleotide binding Database 0.12
Category members GO Category GO:0005506 iron ion binding Database 0.04
Category members GO Category GO:0010181 FMN binding Database 0.04
Category members GO Category GO:0034641 cellular nitrogen compound metabolic process Database 0.01
Category members GO Category GO:0006555 methionine metabolic process Database 0
Category members GO Category GO:0006805 xenobiotic metabolic process Database 0
Category members GO Category GO:0009235 cobalamin metabolic process Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen Database 0
Category members GO Category GO:0032259 methylation Database 0
Category members GO Category GO:0046655 folic acid metabolic process Database 0
Category members GO Category GO:0050661 NADP binding Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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