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Query: MTHFSD

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MTHFSD 0 -0.835 0.660 -0.920

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MTHFSD Phosphorylation S296 -0.835 _RPPDTPGPETNSMEAAPGS(ph)PPGEGAPLAADVYVGNLPR_

Background Information for MTHFSD:





Protein-protein Interactions for MTHFSD

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LRIF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP155 Cat. description Hein, Mann, Cell 2015
Category members IP bait REEP5 Cat. description Hein, Mann, Cell 2015


Protein Domains in MTHFSD

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members FTHF_cligase IPR002698 0.29


Protein complexes (CORUM database) featuring MTHFSD

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MTHFSD

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity Database 0.29
Category members GO Category GO:0009396 folic acid-containing compound biosynthetic process Database 0.09


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