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Query: MTHFS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MTHFS 0 -2.135 1.010 -0.220

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MTHFS Ubiquitylation K76 -2.135 _GK(gl)ICFIPR_

Background Information for MTHFS:





Protein-protein Interactions for MTHFS

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MTHFS Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MTHFS

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members FTHF_cligase IPR002698 0.29


Protein complexes (CORUM database) featuring MTHFS

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MTHFS

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0046653 tetrahydrofolate metabolic process Database 0.91
Category members GO Category GO:0015942 formate metabolic process Database 0.31
Category members GO Category GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity Database 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members Pathway Pathway_275 KEGG_ONE_CARBON_POOL_BY_FOLATE 0 0.11
Category members GO Category GO:0009396 folic acid-containing compound biosynthetic process Database 0.09
Category members GO Category GO:0005542 folic acid binding Database 0


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