bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: MSI2

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MSI2 0 0.577 -0.360 0.880 -0.604 -0.503 -0.428 0.190 0.347

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MSI2 Ubiquitylation K59 -0.142 -0.094 _ECMVMRDPTTK(gl)R_
MSI2 Ubiquitylation K145 -0.244 -0.474 _VEDAMLMFDK(gl)TTNR_

Background Information for MSI2:


Pubmed-MSI2 »
Uniprot-MSI2 »
Biogrid-MSI2 »
ProteomicsDB-MSI2 »

Tumorportal-MSI2 »
COSMIC-MSI2 »
GenomeRNAi-MSI2 »
Genecards-MSI2


Protein-protein Interactions for MSI2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF21A Cat. description Hein, Mann, Cell 2015
Category members IP bait LOXL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MSI2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBFOX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MSI2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34


Protein complexes (CORUM database) featuring MSI2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MSI2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0005844 polysome Database 0.09
Category members GO Category GO:0048864 stem cell development Database 0.03
Category members GO Category GO:0003727 single-stranded RNA binding Database 0
Category members GO Category GO:0008266 poly(U) RNA binding Database 0


.

© Copyright Svejstrup Laboratory 2015