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Query: MORC4

This is a cancer-associated gene according to the Broad cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MORC4 1 -1.727 2.070 -1.170

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MORC4 Ubiquitylation K891 -0.518 -0.230 _ALAK(gl)LTR_
MORC4 Ubiquitylation K403 -0.874 _LNAYWKEK(gl)_
MORC4 Phosphorylation S620 -0.979 _S(ph)TPPYLFPEYPEASK_
MORC4 Phosphorylation T621 -0.979 _S(ph)TPPYLFPEYPEASK_

Background Information for MORC4:


Pubmed-MORC4 »
Uniprot-MORC4 »
Biogrid-MORC4 »
ProteomicsDB-MORC4 »

Tumorportal-MORC4 »
COSMIC-MORC4 »
GenomeRNAi-MORC4 »
Genecards-MORC4


Protein-protein Interactions for MORC4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FAM167A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RYBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YAF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MORC4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members HATPase_C IPR003594 1.07
Category members Prefoldin IPR009053 0
Category members Znf_CW IPR011124 0


Protein complexes (CORUM database) featuring MORC4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MORC4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Human mutations Broad_cancer_genes Broad cancer genes (Lawrence et al., 2014) literature 1.14
Category members GO Category GO:0008270 zinc ion binding Database 0.29


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